everyone is different but if you are prone to addiction being dependent on any substance that gives diminishing returns will always end badly.
i dont use drugs nor do i drink.. they just arent for me and i feel no real need to try them.
but i believe if you are using recreational drugs to help deal with depression and the like, you are just covering up the core issues with a bandage, and in doing so those issues can become a lot worse without you realizing it.